Thar Process is an IP-based single point-of-access for new process development, laboratory-through-process scale-up, and technology licensing.
Supercritical Fluid Extraction
Supercritical fluid extraction (SFE) offers multiple advantages compared to traditional extraction technologies such as organic solvent extraction or distillation. Thar Process Inc. has developed a wide variety of SFE applications in many different areas to satisfy market demand. Thar Process has implemented on a commercial scale truly innovative applications that have resulted in advances in supercritical fluid technology…
SFC or LC - Chromatography
We at Thar Process have a specialized team of professionals who design and fabricate turn-key bio-pharmaceuticals plants for a wide variety of applications, including peptides and insulin. These facilities meet the high regulatory standards of Good Manufacturing Practices (GMP). Our capabilities include the design and fabrication of large-scale chromatography equipment…
Thar Process’s Alternative Energy Division is dedicated to the development of alternative, ‘green’ energy solutions. We have been awarded a grant from the U.S. Government to develop an innovative, continuous biodiesel production process that reduces energy consumption and avoids the use of toxic substances in the production process.
Due to the high diffusivity of supercritical fluids, it is possible to impregnate porous or polymeric media. Using supercritical fluids, impregnation is carried out in two steps. First, the matrix is “soaked” by a supercritical solution of the compound to be impregnated. In the second step, a rapid decompression permits its deposition of the compound while the solvent is rapidly vented in a gas phase. Examples of this concept are:
Polymorph screening. New polymorphs can be found, and previously mixed polymorphs can be purified using supercritical fluid technology. Supercritical fluids open a new dimension, pressure, in the polymorph screening process. Thar Process developed a method and built the first polymorph screening equipment based on a supercritical antisolvent process. This equipment allows the customer to screen polymorphs quickly and effectively.
Supercritical Drying/Solvent Removal
Supercritical drying is commonly used for processing aerogels. Supercritical CO2 can also be used to replace alcohol as the drying medium for wet gels. The absence of surface tension with supercritical fluids allows the gels to be dried with very little shrinkage, resulting in a superior gel matrix that remains nearly intact. As a result, the aerogels formed by supercritical drying have higher surface areas, lower densities, larger pore sizes and greater pore volumes.